Genicular Artery Embolization (GAE) in Manhattan
For many New Yorkers living with chronic knee pain—especially due to osteoarthritis—the traditional options have been limited: medications, injections, physical therapy, or eventually invasive knee replacement surgery. Genicular Artery Embolization (GAE) is an advanced, minimally invasive alternative designed to reduce inflammation, improve mobility, and significantly relieve pain without the risks of major surgery.
At Fox Vein and Vascular, GAE is performed by David Fox, MD, FACS, RPVI a board-certified vascular surgeon with over 28+ years of experience performing image-guided, minimally invasive vascular procedures.

- Minimally invasive treatments
- Board-certified vascular surgeon
- No hospital stay
- Fast recovery
- Personalized care
Patient Testimonials

What Is Genicular Artery Embolization (GAE)?
GAE is a targeted, image-guided procedure that reduces blood flow to areas of the knee that become inflamed in patients who suffer with osteoarthritis. These arteries—called genicular arteries—feed the inflamed synovial membrane surrounding the knee joint.
- Reduces Synovial Inflammation
- Decreases Knee Pain
- Helps Restore Mobility
- Improves Quality Of Life

How Does GAE Work?
GAE’s precision lies in high-definition vascular imaging. Using real-time fluoroscopy (X-ray guidance), Dr. Fox maps the arteries supplying the inflamed areas of the knee. Step-by-step overview:
1. Access
A tiny puncture is made—usually near the ankle or groin—to access an artery. No stitches are required.
2. Catheter Navigation
A slender, flexible catheter is guided through the arterial system to reach the genicular arteries around the knee.
3. Embolization
Microscopic beads (embolization particles) are released into the targeted arteries. These particles:
- Reduce abnormal blood flow
- Lower inflammatory signaling
- Decrease swelling and pain
4. Completion
The catheter is withdrawn, and a small bandage is applied. The entire procedure usually takes 45–90 minutes.
Who Is a Good Candidate for GAE?
GAE is ideal for patients with knee osteoarthritis, especially if they:
- Experience persistent knee pain despite conservative treatments
- Are not ready or not suitable for knee replacement
- Want to avoid steroid injections or cannot receive them
- Prefer a minimally invasive treatment option
- Have failed physical therapy, NSAIDs, viscosupplementation (hyaluronic acid, gel injections, Synvisc, Orthovisc, etc), or PRP
- Have chronic pain that limits daily activities or physical therapy
GAE may NOT be ideal for patients with:
- Active joint infection
- Severe peripheral arterial disease
- End-stage bone-on-bone degeneration; a patient may benefit from imaging review (less likely to work, but we can try it)
A consultation with Dr. Fox—including diagnostic ultrasound and a review of imaging studies—is the best way to determine candidacy.

Advanced Laser Technology for Vein Treatment
GAE has been studied internationally and adopted by leading interventional and vascular specialists.
- Significant reduction in knee pain within weeks of treatment
- Improved function and mobility
- Sustained pain relief lasting 12–24+ months in many patients
- Low complication rates compared to surgical interventions
- High patient satisfaction
Most patients notice an immediate resolution of pain, and others notice improvement within 2–6 weeks, with continued benefits over time as inflammation decreases.
Benefits of Genicular Artery Embolization
Patients choose GAE because it offers:
Minimally invasive treatment—no incisions
Outpatient procedure with same-day discharge
Rapid recovery (often within days)
Significant reduction in pain and inflammation
Non-surgical alternative to joint replacement surgery
No metal implants or removal of tissue
Lower risk than orthopedic surgery
Sustained pain relief lasting 12–24+ months
GAE vs. Other Knee Pain Treatments
| Treatment | Invasiveness | Duration of Relief | Ideal For |
|---|---|---|---|
| GAE | Minimally invasive, catheter-based | Often long-term | OA patients who wish delay or avoid knee replacement surgery |
| Steroid injections | Minimally invasive | Weeks–months | Short-term relief |
| Hyaluronic acid injections | Minimally invasive | Variable | Mild–moderate OA |
| PRP/Stem cell therapy | Minimally invasive | Under study | Some early-stage cases |
| Arthroscopic surgery | Moderately invasive | Limited for OA | Mechanical tears, not OA |
| Total knee replacement | Major surgery | Long-term but major recovery | Severe OA only |
What to Expect During Your GAE Procedure

Before the Procedure
- Consultation and medical evaluation
- Review of imaging studies
- Instructions on medications and hydration
- Procedure is performed with local anesthesia + light sedation

During the Procedure
- You lie comfortably on a procedure table
- Local anesthetic is used at the access site
- Real-time imaging guides catheter placement
- Tiny particles are released with precision
- Most patients feel no significant discomfort

After the Procedure
- You rest briefly in recovery
- Discharged home the same day
- Mild soreness/bruising at the injection site
- Some patients experience a short-lived increase in knee pain
- Most patients resume normal activity in 24–48 hours
Recovery & Results
Timeline of improvement:
- 1–2 days: Return to daily activities
- 2–6 weeks: Noticeable reduction in pain
- 3–6 months: Maximum improvement
- 12–24+ months: Relief often sustained
Most patients can walk, work, and perform light exercise quickly after treatment.
Risks & Safety
GAE is considered safe with a low complication rate. Potential risks may include:
- Temporary skin discoloration
- Bruising at the puncture site
Rare adverse events:
- Transient numbness
- Non-target embolization (minimized through expert imaging)
- Allergic reaction to contrast dye
Dr. Fox’s extensive vascular training and experience helps ensure precise, safe treatment.
A consultation with Dr. Fox — including diagnostic ultrasound and a review of imaging studies — is the best way to determine candidacy.
Why Choose Dr. Fox for Vein
Problems in Manhattan?
Board-Certified Vascular Expertise
Dr. Fox is a board-certified. fellowship-trained vascular surgeon with extensive experience in vein treatment and imaging technology.
Advanced Imaging Technology
Comprehensive Vascular Evaluation
We assess venous and arterial health holistically to ensure optimal outcomes.
Minimally Invasive Philosophy
We specialize in procedures that reduce pain, downtime, and surgical risk.
Personalized Vein Treatment Plans
Every vein procedure is tailored to the individual’s pain pattern, imaging findings, and lifestyle needs.
Frequently Asked Questions
How Long Does The GAE Procedure Take?
Most cases take 45–90 minutes.
Is GAE Painful?
Patients feel little to no discomfort due to local anesthesia and light sedation.
How Soon Can I Walk After GAE?
How Soon Can I Walk After GAE?
Will GAE Cure My Arthritis?
GAE reduces inflammation and pain but has not yet been demonstrated to alter the natural history of osteoarthritis or reverse cartilage loss. It has been proven in multiple clinical studies to improve quality of life and function.
Can I Still Get Knee Replacement Later?
Yes. GAE does not interfere with orthopedic surgery if needed in the future.

David Fox, MD, FACS
- Double Board-Certified Vascular Surgeon
- Attending Vascular Surgeon, Lenox Hill Hospital
Dr. Fox has over two decades of experience diagnosing and treating venous and arterial conditions using the latest minimally invasive techniques. His approach is focused on precision, safety, and helping patients avoid major surgery whenever possible.
Real people. Real results.
Wow What an incredible experience I have nothing short of a glowing review for this practice To begin I was Read More very nervous to have my initial consultation for varicose veins as this kind of stuff makes me pretty uneasy The staff made me feel at ease by explaining how many of these procedures Dr Fox preforms a week Him and his PA Stacey were able to explain the process and procedure in detail while also managing to calm my nerves Crystal who handled insurance approvals and scheduling the procedures was unbelievably accommodating with my tight schedule When I came in for both the EVLT and phlebectomy the staff was so kind and caring even one of the nurses-who always wore a flower in her shirt pocket-offered to hold my hand minutes before being taken into the operating room because she saw how nervous I was I was put to sleep for the - minute procedure so obviously didn't feel a thing I was greeted with a turkey sandwich when I awoke due to needing to fast before the procedure which I thought was a nice touch I felt little to no discomfort after the EVLT and mild to medium discomfort for about a week after phlebectomy Decent bruising for both but is now nearly gone weeks after Highly recommend Dr Fox and his team thank you for making what I thought would be a scary experience into an easy carefree one
I had an amazing experience at Dr Fox's office The staff is nice and helpful They are very organized and Read More everybody is friendly I love the look of the office I didn't have to wait for more than minutes My doctor Dr Jill applied some botox in my face and I am happy with the results I would recommend this to everybody Thank you
I needed to have varicose vein work done on both of my legs during the summer and needed six procedures Read More to complete everything I had been putting it off for a few years but my experience at Fox Vein Care put me totally at ease From the very first consultation until the final procedure Dr Fox his entire staff were kind professional and took care of every step of the way The office was very well clean and well prepared in every way The insurance and financial concerns were handled easily and transparently The medical assistants were awesome and helpful with every process from the front desk to prepping to anesthesia and on into the operating room I am completely satisfied with the results and HIGHLY recommend Fox Vein care as a happy customer
Very good guy and knowledgeable. Very good at following up
Dr. Fox is the best at what he does. He and his staff are phenomenal.
Dr Fox great doctor! Beautiful staff! Clean environment! The best treatment ever...love Dr Fox!!!
I saw Dr Fox last week in his office and I must say I am very impressed and glad I Read More made this choice to see him and I was pleased with the results and treatment options The Whole staff is Amazing Crystal Ben Dr Fox Nicole And everyone else
Excellent patient education and care ESP the doctors surgical coordinator I believe her name is Crystal Attentive reassuring Honest Team Read More as well as Dr Fox was very knowledgeable and caring with my mom thank you so much
David Fox is the best vascular surgeon ever He helped my father with serious issues and his lovely staff really Read More took care of him properly The office is clean and very organized Not only he is amazing in what he does but he is also a caring doctor thank you Fox Vein Care
Dr Fox is excellent at explaining everything that needs to be done during vein procedures His experience and caring nature Read More shine through all interactions Crystal is also wonderful She is always helpful caring and efficient
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