Genicular Artery Embolization (GAE) in Manhattan
A Breakthrough, Minimally Invasive Treatment for Chronic Knee Pain
For many New Yorkers living with chronic knee pain—especially due to osteoarthritis—the traditional options have been limited: medications, injections, physical therapy, or eventually invasive knee replacement surgery. Genicular Artery Embolization (GAE) is an advanced, minimally invasive alternative designed to reduce inflammation, improve mobility, and significantly relieve pain without the risks of major surgery.
At Fox Vein and Vascular, GAE is performed by David Fox, MD, FACS, RPVI a board-certified vascular surgeon with over 20 years of experience performing image-guided, minimally invasive vascular procedures.
Quick 5-Question Self-Assessment
What Is Genicular Artery Embolization (GAE)?
GAE is a targeted, image-guided procedure that reduces blood flow to areas of the knee that become inflamed in patients who suffer with osteoarthritis. These arteries—called genicular arteries—feed the inflamed synovial membrane surrounding the knee joint. By decreasing excessive blood flow, GAE:
Inflammation
Knee Pain
Mobility
Life
GAE is a targeted, image-guided procedure that reduces blood flow to areas of the knee that become inflamed in patients who suffer with osteoarthritis. These arteries—called genicular arteries—feed the inflamed synovial membrane surrounding the knee joint. By decreasing excessive blood flow, GAE:
How Does GAE Work?
GAE’s precision lies in high-definition vascular imaging. Using real-time fluoroscopy (X-ray guidance), Dr. Fox maps the arteries supplying the inflamed areas of the knee.
1
Access
2
Catheter Navigation
3
Embolization
Microscopic beads (embolization particles) are released into the targeted arteries. These particles:
- Reduce abnormal blood flow
- Lower inflammatory signaling
- Decrease swelling and pain
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Completion
Who Is a Good Candidate for GAE?
- Experience persistent knee pain despite conservative treatments
- Are not ready or not suitable for knee replacement
- Want to avoid steroid injections or cannot receive them
- Prefer a minimally invasive treatment option
- Have failed physical therapy, NSAIDs, viscosupplementation (hyaluronic acid, gel injections, Synvisc, Orthovisc, etc), or PRP
- Have chronic pain that limits daily activities or physical therapy
- Active joint infection
- Severe peripheral arterial disease
- End-stage bone-on-bone degeneration; a patient may benefit from imaging review (less likely to work, but we can try it)
Clinical Evidence
Supporting GAE
GAE has been studied internationally and adopted by leading interventional and vascular specialists.
- Significant reduction in knee pain within weeks of treatment
- Improved function and mobility
- Sustained pain relief lasting 12–24+ months in many patients
- Low complication rates compared to surgical interventions
- High patient satisfaction
Most patients notice an immediate resolution of pain, and others notice improvement within 2–6 weeks, with continued benefits over time as inflammation decreases.
Benefits of Genicular Artery Embolization
Patients choose GAE because it offers:
GAE vs. Other Knee Pain Treatments
| Treatment | Invasiveness | Duration of Relief | Ideal For |
|---|---|---|---|
| GAE | Minimally invasive, catheter-based | Often long-term | OA patients who wish delay or avoid knee replacement surgery |
| Steroid injections | Minimally invasive | Weeks–months | Short-term relief |
| Hyaluronic acid injections | Minimally invasive | Variable | Mild–moderate OA |
| PRP/Stem cell therapy | Minimally invasive | Under study | Some early-stage cases |
| Arthroscopic surgery | Moderately invasive | Limited for OA | Mechanical tears, not OA |
| Total knee replacement | Major surgery | Long-term but major recovery | Severe OA only |
What to Expect During Your GAE Procedure
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3
Before the Procedure
- Consultation and medical evaluation
- Review of imaging studies
- Instructions on medications and hydration
- Procedure is performed with local anesthesia + light sedation
During the Procedure
- You lie comfortably on a procedure table
- Local anesthetic is used at the access site
- Real-time imaging guides catheter placement
- Tiny particles are released with precision
- Most patients feel no significant discomfort
After the Procedure
- You rest briefly in recovery
- Discharged home the same day
- Mild soreness/bruising at the injection site
- Some patients experience a short-lived increase in knee pain
- Most patients resume normal activity in 24–48 hours
Recovery & Results
Timeline of improvement:
- 1–2 days: Return to daily activities
- 2–6 weeks: Noticeable reduction in pain
- 3–6 months: Maximum improvement
- 12–24+ months: Relief often sustained
Most patients can walk, work, and perform light exercise quickly after treatment.
Risks & Safety
GAE is considered safe with a low complication rate. Potential risks may include:
- Temporary skin discoloration
- Bruising at the puncture site
Rare adverse events:
- Transient numbness
- Non-target embolization (minimized through expert imaging)
- Allergic reaction to contrast dye
Dr. Fox’s extensive vascular training and experience helps ensure precise, safe treatment.
A consultation with Dr. Fox — including diagnostic ultrasound and a review of imaging studies — is the best way to determine candidacy.
Why Choose Dr. Fox for GAE in Manhattan?
Board-Certified Vascular Expertise
Dr. Fox is a board-certified, fellowship-trained vascular surgeon with extensive experience in
arterial interventions and imaging technology.
Advanced Imaging Technology
We use state-of-the-art fluoroscopy and ultrasound mapping for precise targeting.
Comprehensive Vascular Evaluation
We assess venous and arterial health holistically to ensure optimal outcomes.
Minimally Invasive Philosophy
We specialize in procedures that reduce pain, downtime, and surgical risk.
Personalized Treatment Plans
Every GAE procedure is tailored to the individual’s pain pattern, imaging findings, and lifestyle needs.
Frequently Asked Questions
or reverse cartilage loss. It has been proven in multiple clinical studies to improve quality of life and function.
Schedule a Consultation
Receive expert evaluation and personalized recommendations to relieve your symptoms,
improve circulation, and restore confidence in your legs or hands.
We Accept Most Insurances
We work with most major insurance providers. Contact us to confirm coverage.